This study was aimed to find out the correlation between chemical component contents and physical properties of tanshinone extract powders. The contents of cryptotanshinone and tanshinone IIA from 50 batches of tanshinone extract powders were determined by HPLC. And the physical properties were determined by classical methods. The correlation analysis between component contents and physical properties were also investigated. The results showed that two sets of variables had good intraclass correlation, especially for the contents of cryptotanshinone and tanshinone IIA, among D10, D50, D90, there were relatively strong correlation between the bulk density and tapped density, between the Hausner ratio and compressibility index. The angle of repose had a certain correlation with the uniformity, Hausner ratio and compressibility index, but with no strong correlation. The correlation coefficient between two sets was below 0.400, suggesting there was a not so good inter-group correlation. After the canonical correlation analysis, three pairs of canonical variables had significant correlations with correlation coefficients being 0.851, 0.674 and 0.565, respectively. It was concluded that there was a good intraclass correlation for each of physical and/or chemical quality set, but the correlation between the two sets was bad. Canonical variables performed better inter-group correlation compared with original variables, indicating there was a certain correlation between chemical and physical quality attributes of tanshinone extract powders.